Ischemic Heart Disease
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چکیده
Ischemic heart disease (IHD) is the generic designation for a group of closely related syndromes resulting from myocardial ischemia—an imbalance between the supply (perfusion) and demand of the heart for oxygenated blood. Ischemia comprises not only insufficiency of oxygen, but also reduced availability of nutrient substrates and inadequate removal of metabolites (see Chapter 1 ). Isolated hypoxemia (i.e., diminished transport of oxygen by the blood) induced by cyanotic congenital heart disease, severe anemia, or advanced lung disease is less deleterious than ischemia because perfusion (including metabolic substrate delivery and waste removal) is maintained.
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